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HomeMedical Information CancerWhen Stage 0 Breast Cancer Isn’t Good News

When Stage 0 Breast Cancer Isn’t Good News

By: Medix Team

New study finds that women with ductal carcinoma in situ (DCIS) are at a higher-than-normal risk of death, overturning previous thinking on the subject.

One of the earliest and most treatable forms of breast cancer poses a three-fold higher risk of death than normal according to a new study published by JAMA Network Open.

 

Researchers analysed 144,000 US women who’d been diagnosed with ductal carcinoma in situ (DCIS) over a 19-year period. This is a stage 0 breast cancer that’s often referred to as a pre-cancer, or a non-invasive cancer since cancerous cells have formed in the lining of the milk ducts but not yet spread to breast tissue.

 

Their findings are likely to change the way the disease is viewed since it shows that DCIS is far more dangerous the oncologists previously believed. The researchers also discovered that the earlier a woman is diagnosed, the higher the risk: 12 times higher than normal for women under 40 and three times higher overall.

 

All of the women had undergone surgery either in the form of a lumpectomy, or a mastectomy. The researchers concluded that since this did not completely eliminate risk, it is important that women who’ve had a DCIS diagnosis continue to receive regular screening for breast cancer.

 

They also recommended that women discuss treatments, which may reduce the likelihood of disease recurrence (like Tamoxifen and Radiotherapy) with their doctors. There is also a genetic test called Oncotype DX DCIS, which can help determine the likelihood of recurrence and aid treatment options.

 

The full report can be read here: https://jamanetwork.com/journals/jamanetworkopen/article-abstract/2770653

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